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NAD+

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NAD+, or nicotinamide adenine dinucleotide, is a molecule necessary for the function of every cell in the body. The molecule is a cofactor for many enzymatic reactions within the body. It is crucial for mitochondrial function. The mitochondria are the organelles in our cells that produce ATP, which is the molecule that gives us energy. As we age our levels of NAD+ naturally decrease and energy levels typically drop. 

NAD+ is an oxidized form of NADH which is necessary to breakdown food from large molecules (proteins, carbohydrates, and fats) to smaller molecules that our body can use. NADH is needed to repair DNA, and create ATP for our cells to function properly. Our bodies do not have an endless supply of NAD+ and the amount of the molecule decreases while we age. Also, chronic stress and the use of drugs and alcohol can decrease levels of NAD+.

Cells with highest concentration for NAD+ are cardiac/heart tissue, brain, and muscle tissue. These tissues are typically targeted with therapy. However, every cell in the body can benefit from increased levels of NAD+.

Benefits of NAD+

  • Helps repair damaged DNA

  • Increased Energy

  • Anti-aging 

  • Protective for brain health

  • Improves cellular ATP levels 

  • Prevention from chronic disease

 

Conditions Commonly Treated with NAD+

  • Anxiety / Depression 

  • Neurodegenerative Disorders: Alzheimer's, Dementia, Parkinson's Disease 

  • Fatigue / CFS, Adrenal Fatigue

  • Alcohol or drug Addiction / Abuse 

  • Anti-Aging / Regenerative Medicine

  • Fibromyalgia 

  • Weight Loss/ Metabolic disorders

What to expect?

NAD+ Therapy is an IV procedure that can greatly vary on the length of time for each individual. Some people can tolerate 250-500mg doses in 1-3 hours whereas others may take up to 4-5 hours for the same dose. Possible side effects may include rapid heart beat, heart palpitation, mild chest pain, sweating, anxiety and/or nausea. However, we infuse our IVs with the utmost care to make sure that you do not experience these side effects.  Because the therapy can take a long time we recommend bring something to snack on while you are completing your infusion. 

Contraindications of NAD+

  • Known or untreated cancer

  • Unstable heart condition

 

Nicotinamide adenine dinucleotide (NAD+) is a coenzyme present in all living cells that plays a critical role in the chemical processes that generate energy within the body. It has gained attention for its potential health benefits, particularly as we age and our natural levels of NAD+ decline. Here's how NAD+ can help:

  1. Boosts Metabolism: NAD+ is essential for metabolic processes, helping to convert food into the energy that powers cells. Supplementing with NAD+ or boosting its levels can potentially enhance metabolic function, leading to improved energy levels and possibly aiding in weight management.

  2. Supports Cellular Repair: NAD+ plays a significant role in DNA repair and the maintenance of cell health. It activates enzymes that may help prevent aging cells from becoming dysfunctional, which is crucial for reducing the risk of age-related diseases.

  3. Improves Brain Health: NAD+ has been shown to support brain function and cognitive health. It helps in maintaining the health of neurons and stimulating the production of neurotransmitters. Higher levels of NAD+ are associated with improved memory, focus, and mood.

  4. Enhances Mitochondrial Function: Mitochondria, the "powerhouses" of cells, rely on NAD+ to generate energy. By supporting mitochondrial function, NAD+ supplementation can help improve energy levels, reduce fatigue, and potentially slow down the aging process of cells.

  5. May Extend Lifespan: Research, particularly in animal models, suggests that increasing NAD+ levels can activate sirtuins, a group of proteins linked to aging. Activation of sirtuins has been associated with increased lifespan and improved health during aging, though more research is needed to fully understand this effect in humans.

  6. Supports Heart Health: NAD+ can improve cardiovascular health by enhancing the function of the endothelium (the lining inside blood vessels) and reducing oxidative stress, which in turn can lower blood pressure and reduce arterial stiffness.

  7. Improves Muscle Health: As we age, muscle function declines partly due to decreased mitochondrial function. NAD+ helps maintain mitochondrial health, which can support muscle strength, endurance, and recovery.

  8. Detoxification and Repair: NAD+ is involved in the body’s internal repair mechanisms, including detoxifying harmful substances. It plays a role in the activation of enzymes that metabolize alcohol and other toxins, supporting liver health and systemic detoxification processes.

  9. Potential in Treating Addiction: Preliminary research suggests that NAD+ therapy may help reduce withdrawal symptoms and cravings associated with substance abuse, making it a potential tool in addiction recovery programs.

  10. Regulates Circadian Rhythms: NAD+ levels fluctuate throughout the day, impacting circadian rhythms and sleep patterns. Maintaining optimal NAD+ levels can help regulate these biological clocks, potentially improving sleep quality and overall health.

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